CHKBiotech idapanga bwino zida zodziwira mitundu yatsopano ya coronavirus

New Coronavirus Variant Strain 501Y-V2 yaku South Africa
Pa Disembala 18, 2020, South Africa idapeza kusintha kwa 501Y-V2 kwa coronavirus yatsopano.Tsopano mtundu wamtunduwu wa ku South Africa wafalikira kumayiko oposa 20.Kuyesera kwawonetsa kuti pamwamba pa New Corona-virus Mutants imatha kunyamula mitundu ina ya New Coronavirus ya K417N/T, E484K ndi N501Y masinthidwe omwe atha kuchepetsa mphamvu yochepetsetsa ya ma antibodies oyambitsa katemera a plasma.Komabe, poyerekezera ndi ma genome a Wuh01 (nambala yotsatizana MN908947), 501Y.V2 ya ku South Africa mutant genome sequence ili ndi 23 nucleotide mitundu.Ili ndi masinthidwe a N501Y omwewo ngati a Britain mutant B.1.1.7 sub-type, komabe imakhala ndi masinthidwe pamasamba awiri ofunikira E484K ndi K417N ya mapuloteni a S omwe ali ndi zotsatira zofunikira pakutha kwa kachilomboka.

Coronavirus Watsopano ndi kachilombo ka RNA yokhala ndi chingwe chimodzi, chomwe masinthidwe a Genome amakhala pafupipafupi.Kuzindikira chandamale chimodzi kungayambitse kuphonya kwa zitsanzo zokhala ndi ma virus ochepa komanso ma virus osinthika.Mlingo wowunikiranso pachokhachokha pakuzindikiritsa chandamale, ukhoza kufika kupitilira 10%, zomwe zitha kuwonjezera kuchuluka kwa ntchito ndikutalikitsa nthawi yozindikira.Kuzindikira zolinga zambiri ndi kutsimikizirana kwa zotsatira za cholinga chilichonse kungathe kuonjezera chiwerengero cha kuzindikira ndikuthandizira kuzindikira msanga.

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Chithunzi 1. Chithunzi chojambula cha New Coronavirus imakina

New Coronavirus Mutant B.1.1.7 waku Britain
Pa Disembala 26, 2020, pepala loyamba la sayansi la B.1.1.7 Strain lidasindikizidwa pa intaneti.Institute of Hygiene University of London UK ndi Tropical Diseases, adatsimikizira kuti B.1.1.7 Strain imatha kufalikira kuposa zovuta zina, zomwe zinali zoposa 56% (95% CI 50-74%).Chifukwa mtundu watsopano wosinthikawu uli ndi mphamvu zowonekera bwino, zakhala zovuta kuwongolera COVID-19.Tsiku lotsatira, yunivesite ya Birmingham ku United Kingdom inakweza nkhani ya MedRxiv.Kafukufukuyu anapeza kuti chiwerengero cha ORF1ab ndi N kachilombo ka HIV kwa odwala omwe ali ndi vuto la B.1.1.7 mutant strain (S-gene dropout) anawonjezeka kwambiri;chodabwitsa ichi chinali kuyang'aniridwa mwa anthu.Nkhaniyi ikusonyeza kuti odwala omwe ali ndi kachilombo ka B.1.1.7 ku Britain ali ndi kachilombo koyambitsa matenda kwambiri, kotero kuti kusintha kumeneku kungakhalenso koyambitsa matenda.

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Chithunzi 2. Mndandanda wa masinthidwe amtundu womwe uli mumtundu wa coronavirus mutant B.1.1.7 waku Britain

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Chithunzi 3. Kusintha kwa N501Y kunachitika ku Britain ndi ku South AfricaZosintha

Zida Zodziwira Zamitundu Yatsopano ya Coronavirus
Chuangkun Biotech Inc. yapanga zida zodziwira bwino za B.1.1.7 ndi 501Y-V2 zatsopano za coronavirus.

Ubwino wa mankhwalawa: kukhudzika kwakukulu, kuzindikira kwanthawi imodzi kwa zolinga zinayi, kuphimba malo akuluakulu osinthika a B.1.1.7 mutant strain ndi 501Y.V2 South Africa mutant strain.Chidachi chimatha kuzindikira nthawi imodzi malo osinthika a N501Y, HV69-70del, E484K ndi jini yatsopano ya coronavirus S;Kuyesa mwachangu: zimangotenga ola limodzi ndi mphindi 30 kuchokera pakutolera zitsanzo kuti zitheke.

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Chithunzi 4. Kuzindikira kwa COVID-19 Britain Variant Amplification Curve

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Chithunzi 5. Kuzindikira kwa COVID-19 South African Variant Amplification Curve

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Chithunzi 6. Mtundu wakutchire wa New coronavirus amplification curve

Sizikudziwika bwino momwe masinthidwewa amapezera zotsatira za nthawi yayitali za mliri wa COVID-19.Koma izi zikutikumbutsa kuti masinthidwewa amatha kukhudza mphamvu ya chitetezo chamthupi komanso chitetezo chokwanira chomwe chimadza chifukwa cha katemera.Zikutikumbutsanso kuti tiyenera kuyang'anira nthawi zonse kachilombo ka corona kwa nthawi yayitali ndikusintha katemera wa COVID-19 kuti athane ndi kusinthika kwa coronavirus yatsopano.


Nthawi yotumiza: Mar-12-2021